Peyton Manning's 3 interceptions still couldn't derail the Indianapolis Colts' perfect season. The Colts moved to 13-0 defeating the Denver Broncos 28-16.  Manning also added 4 touchdowns to offset his 3 interceptions while Denver's Brandon Marshall grabbed 21 catches for 200 yards and 2 touchdowns in a losing effort. The league's other undefeated squad remained that way as the New Orleans Saints survived at Atlanta 26-23 to match Indy's 13-0 mark. Drew Brees continued his impressive year adding 296 yards and 3 touchdowns while his counterpart Chris Redman threw for 303 yards and a touchdown in a loss for the Falcons.

Other winners around the league included, Buffalo, Jets, San Diego, Minnesota , Baltimore, Green Bay , Tennessee, Washington, Philly, New England, and Houston. In Jacksonville the Miami Dolphins improved their playoff chances by upsetting the Jaguars 14-10 moving their record to 7-6. Monday nights match-up sees the Arizona Cardinals at the San Fransisco 49er's. The odds makers have the visiting Cardinals as a 3 point favourite.